Malassezia have lost a gene* required to completely burn unsaturated fats—but they can burn saturated fats without issue. This means they...

Malassezia are very picky eaters. They can’t grow if given only short fatty acids, probably because they can’t elongate them to build...

Malassezia are lipid dependent fungi which require human fat to grow in our bodies. This is quite unusual for fungi: all other medically...

Many lipid metabolism alleles are risk factors of Parkinson’s disease (Xicoy 2019). Individuals who inherit non-functional GBA variants...

Seborrheic dermatitis is a type of skin inflammation caused by overgrowth of Malassezia (Borda 2015). It has long been known to be...

To keep commensal microbes in check and fight off infections, our immune system relies heavily on helper T cells. In the Parkinson’s...

In 2012, the discovery that PSP94 was a fungicidal protein firmly pointed to a fungal cause for prostate cancer (Stott-Miller 2013,...

Mycobacterium avium subspecies paratuberculosis (MAP) is an important trigger for Crohn’s disease. However, most Crohn’s patients don’t...

Many studies report that antifungal drugs can be effective in treating advanced prostate cancer (Trachtenberg et al 1984; Mahler et al...

Chronic inflammation of the prostate Chronic inflammation of the prostate is very common, affecting between 15% and 40% of adult...

The PSP94 Project started at the beginning of 2012, when it was discovered that a human protein called PSP94 is a potent fungicide...

This post is a detailed explanation of the animated back pain video. Back pain (AS-type) Ankylosing spondylitis (AS) is a common type of...

HLA-B27 and CARD9 gene variants increase the risk of spondyloarthropathies, and point to a chronic fungal infection as the main cause of...

Genetics of spondyloarthropathies Immune system genes play an extremely important role in spondyloarthropathies. Epidemiologists knew...

A severe form of chronic inflammatory back pain is called ankylosing spondylitis (AS), where damage to joints separating vertebrae can be...

Candida in the gut are associated with psoriasis and atopic dermatitis The presence of Candida in the gut is associated with both...

T cells originating in the gut can cause psoriasis T cells in psoriatic skin often originate in the gut. We know this because they...

Psoriasis and Candida: the problem In 1925, Fleisher and Wachowiak discovered that psoriasis patients had high rates of Candida in their...

Microbes which live on our skin have long been suspected of contributing to chronic inflammation, in particular seborrheic dermatitis,...