In 2012, the discovery that PSP94 was a fungicidal protein firmly pointed to a fungal cause for prostate cancer (Stott-Miller 2013, Sutcliffe 2014). Since th...

Mycobacterium avium subspecies paratuberculosis (MAP) is an important trigger for Crohn’s disease. However, most Crohn’s patients don’t have MAP, thus will n...

Many studies report that antifungal drugs can be effective in treating advanced prostate cancer (Trachtenberg et al 1984; Mahler et al 1993; Small et al 2004...

Chronic inflammation of the prostate Chronic inflammation of the prostate is very common, affecting between 15% and 40% of adult men—depending on age groups ...

The PSP94 Project started at the beginning of 2012, when it was discovered that a human protein called PSP94 is a potent fungicide (Edstrom et al 2012). The ...

This post is a detailed explanation of the animated back pain video. Back pain (AS-type) Ankylosing spondylitis (AS) is a common type of spondyloarthropathy w...

HLA-B27 and CARD9 gene variants increase the risk of spondyloarthropathies, and point to a chronic fungal infection as the main cause of symptoms (see here f...

Genetics of spondyloarthropathies Immune system genes play an extremely important role in spondyloarthropathies. Epidemiologists knew this well before we cou...

A severe form of chronic inflammatory back pain is called ankylosing spondylitis (AS), where damage to joints separating vertebrae can be seen on X-rays. Les...

Candida in the gut are associated with psoriasis and atopic dermatitis The presence of Candida in the gut is associated with both psoriasis (Fleisher et al 1...

T cells originating in the gut can cause psoriasis T cells in psoriatic skin often originate in the gut. We know this because they express ⍺Eβ7 integrin, a m...

Psoriasis and Candida: the problem In 1925, Fleisher and Wachowiak discovered that psoriasis patients had high rates of Candida in their guts as compared to ...

Microbes which live on our skin have long been suspected of contributing to chronic inflammation, in particular seborrheic dermatitis, psoriasis and atopic d...

I read "Can You Outsmart an Economist?" by Steven Landsburg last week. It’s a very entertaining book, large portions of which are dedicated to explaining how...

In 1981, a young Australian doctor named Barry Marshall used a microscope to detect Helicobacter pylori in stomach biopsies of gastric ulcer patients. We now...

In 2010, Samuel and colleagues published a small retrospective study describing five Crohn’s patients who had contracted the soil fungus Histoplasma capsulat...

Effective altruism is what motivated The Malassezia Project. The rationale and potential impact of this project are explained in this post, which first appea...

I've been preparing The Malassezia Project website and videos for four months, and am glad it's finally done! This site is an accessible and simplified summa...